Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” in Amendment No.1 to the Registration Statement (Form F-1 No. 333-265159) and related Prospectus of TC BioPharm (Holdings) Plc for the registration of American Depositary Shares and to the incorporation by reference therein of our report dated May 13, 2022 with respect to the consolidated financial statements of TC BioPharm (Holdings) Plc, included in its Annual Report (Form 20-F) for the year ended December 31, 2021, filed with the Securities and Exchange Commission.